If you wish to update the program from two update servers, then it is necessary to create two different update profiles. If the first one fails to download update files, then the program automatically switches to the alternative one. This is suitable for example for notebooks, which normally update from a local LAN update server, but their owners often connect to the Internet in other networks. So if the first profile fails, the second one will automatically download update files from ESET’s update servers.
More information about update profiles you find in Update profiles