List of keyboard shortcuts available from within the ESET NOD32 Antivirus user interface:
| Keyboard Shortcut | Description |
| Ctrl + G | toggles between graphical and text mode |
| Ctrl + I | opens ESET SysInspector |
| Ctrl + L | opens Log files |
| Ctrl + M | toggles between Standard and Advanced display mode |
| Ctrl + Q | opens Quarantine |
| Ctrl + R | resets window layout to the default state |
| Ctrl + S | opens Scheduler/Planner |
| Ctrl + U | opens the Username and Password setup dialog |
| F1 | opens Help pages |
| Ctrl + F1 | opens Help pages index |
| Ctrl + Shift + F1 | opens Help pages search |
| F5 | opens Advanced setup |